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V Bindokas and The Integrated Light Microscopy Core at The University of Chicago for the assistance with confocal imaging and analysis

All participants gave written informed consent before enrollment into the study

Consequently, many GSH-responsive nanoplatforms are designed either to deplete GSH by targeting these pathways or to exploit high GSH levels as triggers for selective drug release

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The investigators observed that epithalon treatment was associated with activation of telomerase and measurable elongation of telomeres in cultured fetal fibroblast cells that had reached near-replicative senescence